Among these three grim hypotheticals, the least unsurvivable is the third: sodium and chlorine in amounts that would together make 50 grams of sodium chloride, taken sequentially. That conclusion owes nothing to chemical elegance and everything to arithmetic. Fifty grams of table salt contains only about 19.7 grams of sodium and 30.3 grams of chlorine by mass. Those are still dangerous quantities in elemental form, though they are markedly less extreme than swallowing 50 grams of sodium metal or 50 grams of chlorine itself.
Elemental sodium is the clearest loser. It is not simply “a lot of sodium” in the dietary sense. It is a soft alkali metal that reacts violently with water, generating heat and caustic sodium hydroxide, with hydrogen gas as a by-product. The mouth, oesophagus and stomach are wet environments, so ingestion would amount to a chemical reaction inside living tissue. One would expect burns, perforation, and potentially catastrophic thermal and caustic injury before the body’s electrolyte balance even became the central issue. “Fifty grams” here is an absurdly large amount: nearly a mole of sodium metal, enough to make the chemistry itself the emergency.
Chlorine presents a different problem. At ordinary temperatures it is a gas, which makes the phrase “ingesting chlorine only” slightly unstable unless one imagines liquid chlorine, chlorine dissolved in water, or some contrived containment. Toxicology treats chlorine chiefly as an inhalation hazard. It is intensely irritating and corrosive to the eyes, airways and lungs; high exposures can produce pulmonary oedema and acute respiratory compromise. If somehow swallowed in a concentrated form, the damage would still be corrosive, though practical ingestion is less straightforward than with sodium or salt. In other words, chlorine is a murderous substance, yet the route of exposure in the question is chemically awkward.
The third option is the one that feels almost civilised by comparison, though only by comparison. To make 50 grams of sodium chloride requires about 19.7 grams of elemental sodium and 30.3 grams of chlorine. If these are taken sequentially rather than reacted safely in a flask, the first material would already have had its say before the second arrived. The body is not a beaker. Any hope that sodium and chlorine might obligingly meet and neutralise each other inside the digestive tract ignores the violence and tissue damage caused by each on contact. Sequential exposure therefore remains extremely dangerous. Yet if one insists on ranking survivability, lower mass of each elemental substance generally improves the odds relative to the 50-gram elemental exposures.
A more interesting comparison is between option three and simply swallowing 50 grams of sodium chloride. Even table salt at that level can be life-threatening. Acute salt poisoning can drive severe hypernatraemia, seizures and death, especially if taken quickly or in vulnerable people. Reports in the medical literature suggest that adult fatalities have occurred at surprisingly modest acute doses, and a systematic review found that many severe acute salt ingestions had fatal outcomes. So the benign familiarity of salt should not mislead. Chemistry turns on form as much as composition: sodium in a crystal lattice with chloride is a commonplace nutrient; sodium as a reactive metal is an altogether different proposition.
The sober answer, then, is that none is meaningfully “survivable” in the everyday sense. If forced into a ranking, the best chance belongs to the sequential amounts that sum to 50 grams of sodium chloride, then chlorine alone, then sodium alone as the most immediately catastrophic. That ordering reflects practical toxicology rather than any comforting notion that the body can perform neat little acts of synthesis under duress. It cannot. It suffers the chemistry first.
Citations: CDC/NIOSH chlorine guidance and IDLH documentation; CDC chlorine fact sheet; PubChem chemical hazard information on chlorine-related compounds; NCBI and PubMed reviews on acute salt toxicity and fatal hypernatraemia.